BIOPHYSICS OF THE CARDIOVASCULAR SYSTEM: MECHANISMS, MATHEMATICAL MODELS AND CLINICAL ASPECTS
Feruza Baxtiyarovna Nurmatova
Ulugbek Ismailov
second-year student Tashkent State Medical University
Keywords: biophysics, heart, vessels, hemodynamics, mathematical modeling, electrical activity, arrhythmia, cardiology.
Abstract
This article examines the biophysical mechanisms of the human cardiovascular system, including the electrical activity of cardiomyocytes, the hydrodynamic patterns of blood flow, and the mechanical properties of the vascular wall. Modern mathematical models used in medical biophysics are presented: the Hodgkin-Huxley model, the FitzHugh-Nagumo model, the Poiseuille and Wintrich equations, and three-chamber heart models. Particular attention is paid to the clinical aspects of biophysical processes—diagnosis of cardiovascular diseases, hemodynamic analysis, arrhythmia prediction, and evaluation of the effectiveness of drug and surgical interventions. This work emphasizes the importance of biophysical approaches in modern clinical medicine and the development of evidence-based diagnostic methods.
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