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ZENODO
Published
2025-11-05
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Articles
How to Cite
How to Cite
ALAI MUMIYO (SHILAJIT): TRADITIONAL ORIGINS AND EXPERIMENTAL EVIDENCE OF ANTICOAGULANT AND FIBRINOLYTIC ACTIVITY
Zagrutdinov Fanil
Andijan State Medical Institute, Department of Pharmacology, Clinical Pharmacology, and Medical Biotechnology.
Keywords: Alai mumiyo, blood coagulation, dogs, anticoagulant activity, fibrinolysis, fibrinogen, thrombin time, natural extract.
Abstract
The effect of Alai mumiyo extract (25 mg/kg) on blood coagulation in dogs was studied. Ten healthy animals received the extract orally, and coagulation parameters were measured at baseline, 30, and 60 minutes. The extract significantly prolonged clotting, recalcification, and thrombin times, increased plasma tolerance to heparin, and enhanced fibrinolytic activity (p < 0.05). Fibrinogen levels slightly decreased, while coagulation factor activities and total protein remained unchanged. Alai mumiyo exhibits anticoagulant and fibrinolytic effects, indicating potential for natural modulation of hemostasis.
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