PDF
ZENODO
Published
2025-10-14
Section
Articles
How to Cite
How to Cite
BIOLOGICALLY ACTIVE COMPOUNDS OF LALLEMANTIA ROYLEANA (BENTH.) BENTH. AND THEIR SIGNIFICANCE IN MODERN MEDICINE
Pulatova Aziza Ramazon kizi
1Department of Botany and Genetics, National University of Uzbekistan, Tashkent, Uzbekistan
Makhkamov Trobjon Khusanboyevich
2Department of Forestry and Landscape Design, Tashkent State Agrarian University, Kibray district, Tashkent region, Uzbekistan
Allaberdiyev Rustamjon Khamrayevich
1Department of Botany and Genetics, National University of Uzbekistan, Tashkent, Uzbekistan
Keywords: Uzbekistan, Lallemantia royleana, essential oil, GC-MS, citral, ocimene, hydrocarbons, phytotherapy, aromatic compounds.
Abstract
This study presents the results of a comprehensive investigation into the chemical composition of the essential oil extracted from the aerial parts of Lallemantia royleana (Benth.) Benth. The qualitative and quantitative analysis of the volatile constituents was performed using gas chromatography coupled with mass spectrometry (GC–MS). The plant material was collected during the active vegetative growth phase in May 2024 from the experimental plot of the Botanical Garden of the National University of Uzbekistan named after Mirzo Ulugbek (Tashkent city). A total of 70 volatile compounds were identified, forming the chemical profile of the essential oil.
The major constituents of the oil were β-ocimene (15.67%), citral (12.59%), nerol (12.72%), and β-citral (9.15%). These compounds exhibit significant biological activities, including antimicrobial, antioxidant, and anti-inflammatory effects, which support the potential of L. royleana as a valuable source of natural bioactive substances.
The high content of monoterpenes and aldehydes in the essential oil highlights its aromatic and therapeutic properties, opening up broad prospects for its use in the pharmaceutical, food, cosmetic, and perfume industries. The findings confirm the significant potential of L. royleana as medicinal and technical raw material and emphasize the need for further research focused on standardization, biological evaluation, and industrial application of its essential oil.
References
1. Bozorgi M., Vazirian M. Antioxidant activity of Lallemantia royleana (Benth.) seed extract //Traditional and integrative Medicine. – 2016. – S. 147-150.
2. Al-Snafi A. E. Pharmacological and Therapeutic effects of Lallemantia royleana-A review //IOSR Journal of Pharmacy. – 2019. – T. 9. – №. 6. – S. 43-50.
3. Sardarodiyan M. et al. Antioxidant and antimicrobial activities of water-soluble polysaccharide isolated from Balangu seed (Lallemantia royleana) gum //Journal of Analytical Science and Technology. – 2019. – T. 10. – S. 1-11.
4. Mahmood S. et al. Antibacterial activity of Lallemantia royleana (Benth.) indigenous to Pakistan //Afr J Microbiol Res. – 2013. – T. 7. – №. 31. – S. 4006-4009.
5. Saleem A. et al. Therapeutic Role of Lallemantia royleana (Balangu Seeds) and Its Pharmacological Properties: An Overview //Sch Bull. – 2022. – T. 8. – №. 9. – S. 283-287.
6. Ghannadi A., Movahedian A., Jannesary Z. Hypocholesterolemic effects of Balangu (Lallemantia royleana) seeds in the rabbits fed on a cholesterol-containing diet //Avicenna Journal of Phytomedicine. – 2015. – T. 5. – №. 3. – S. 167.
7. Massey S. et al. Preparation, characterization and biological evaluation of silver nanoparticles and drug loaded composites for wound dressings formed from Lallemantia royleana seeds’ mucilage //Journal of Biomaterials Science, Polymer Edition. – 2022. – T. 33. – №. 4. – S. 481-498.
8. Atabaki R., Hassanpour-Ezatti M. Improvement of lidocaine local anesthetic action using Lallemantia royleana seed mucilage as an excipient //Iranian Journal of Pharmaceutical Research: IJPR. – 2014. – T. 13. – №. 4. – S. 1431.
9. Ghannadi A., Zolfaghari B. Compositional analysis of the essential oil of Lallemantia royleana (Benth. in Wall.) Benth. from Iran //Flavour and fragrance journal. – 2003. – T. 18. – №. 3. – S. 237-239.
11. https://pubchem.ncbi.nlm.nih.gov/compound/Citral
12. https://pubchem.ncbi.nlm.nih.gov/compound/Nerol
13. https://pubchem.ncbi.nlm.nih.gov/compound/beta-OCIMENE
