BRONCHIAL ASTHMA: CLINICAL FEATURES, DIAGNOSTIC CRITERIA, AND MODERN TREATMENT STRATEGIES
Sayfiddinova Muhayyo
Termez branch of Tashkent medical academy
Norpulatova Moxira
Termez branch of Tashkent medical academy
Ismoilov Muxammadali
Termez branch of Tashkent medical academy
Keywords: Bronchial asthma, airway inflammation
Abstract
Bronchial asthma remains one of the most prevalent and socially significant chronic respiratory diseases worldwide. According to the World Health Organization (WHO), asthma affects approximately 262 million people and caused over 461,000 deaths in 2019 alone. Despite advancements in medical technology, pharmacotherapy, and improved global access to healthcare, bronchial asthma continues to represent a major public health burden, particularly due to its chronic nature, rising incidence in both developed and developing countries, and the substantial economic impact of its management.
References
1. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention — 2023 Update. Available from: https://ginasthma.org
2. World Health Organization. Asthma: Key facts. Geneva: WHO; 2023. Available from: https://www.who.int/news-room/fact-sheets/detail/asthma
3. Boulet LP, Reddel HK, Bateman ED, et al. The evolution of asthma guidelines: A global perspective. Lancet Respir Med. 2022;10(3):233–244.
4. Holguin F, Cardet JC, Chung KF, et al. Management of severe asthma: A European Respiratory Society/American Thoracic Society guideline. Eur Respir J. 2020;55(1):1900588.
5. Pavord ID, Beasley R, Agusti A, et al. After asthma: Redefining airways diseases. Lancet. 2018;391(10118):350–400.
6. Hanania NA, Wenzel S, Rosén K, et al. Exploring the efficacy and safety of dupilumab in patients with uncontrolled persistent asthma: Lancet. 2016;388(10039):31–44.














