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2025-04-04
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IMPACT OF VARIOUS ANTIHISTAMINES ON CHANGES IN THE ACTIVITY OF PANCREATIC DIGESTIVE ENZYMES OF THE RAT AGAINST THE BACKGROUND OF ANAPHYLACTIC SHOCK
Ismoilov S.R
Urgench branch of the Tashkent medical Academy, Department of pharmacology and clinical pharmacology. Urgench, Uzbekistan
Ismailov A.U
Urgench branch of the Tashkent medical Academy, Department of pharmacology and clinical pharmacology. Urgench, Uzbekistan
Omonova G.S.
Urgench branch of the Tashkent medical Academy, Department of pharmacology and clinical pharmacology. Urgench, Uzbekistan
Karimova D.Sh.
Urgench branch of the Tashkent medical Academy, Department of pharmacology and clinical pharmacology. Urgench, Uzbekistan
Keywords: antihistamines, anaphylactic shock
Abstract
It was found that against the background of anaphylactic shock, noticeable changes occur in the spectrum of activity of pancreatic enzymes, which can affect the breakdown and assimilation of the main components of food. Antihistamines (dimedrol, diazoline, suprastin, fenkarol, zaditen), introduced in the process of causing anaphylactic shock, significantly correct the observed changes in the activity of the studied enzymes. The effectiveness of the corrective action of fenkarol and, especially, zaditen, are superior to other remedies.
References
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